Ultrastructural Alterations in Liver of Medaka (Oryzias latipes) Exposed to Diethylnitrosamine
نویسندگان
چکیده
منابع مشابه
Circadian variations in the liver metabolites of medaka (Oryzias latipes)
Circadian rhythms are biological rhythms with a period of around 24 hours. In this study, we compared the metabolome of the liver of medaka during the day and night. To comprehensively analyze the circadian variations in the levels of metabolites in the liver, livers were isolated from Zeitgeber time (ZT)4 and ZT16, and the variations in metabolite levels were evaluated. Inosinemonophosphate (I...
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A recent study in our laboratory has demonstrated that tetrachloroethylene (TCE) is acutely toxic to Japanese medaka (Oryzias latipes) larvae with a 96 hr-LC50 of 18 (17-19) mg/mL (Spencer et al., 2002). In the present study we hypothesize that TCE exposure induces a developmental effect in Japanese medaka. Growth and age specific sensitivity of Japanese medaka larvae were studied with four age...
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Japanese medaka (Oryzias latipes), a small freshwater fish used extensively to investigate sexual differentiation and development, were exposed to octylphenol (OP), a known estrogen agonist, to assess its impact on reproductive success. Male and female medaka were exposed to nominal concentrations of 10, 25, 50, and 100 mg/L OP from 1 d posthatch to 6 months posthatch. In reproduction trials in...
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The recently developed female leukophore-free (FLFII) strain of Japanese medaka (Oryzias latipes) carries DNA markers for the identification of genotypic sex. Information regarding genotypic sex is useful for tests in which endocrine-disrupting compounds may masculinize or feminize fish. In the present study, methods were developed to automate DNA extraction and profiling for rapid determinatio...
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ژورنال
عنوان ژورنال: Toxicologic Pathology
سال: 1992
ISSN: 0192-6233,1533-1601
DOI: 10.1177/019262339202000205